CFB 10* Top Play
(NCAAF) Pittsburgh vs. Michigan State, 12/30/2021 7:00 PM, Score: 21 - 31
Point Spread: 3.50 | -110.00 Pittsburgh (Away)
Result: Loss
Michigan State vs. Pittsburgh 7:00 PM ET
Game# 259-260
Play On: Pittsburgh +3.5 (10*)

Both teams will be without their top offensive player. Pitt quarterback Kenny Pickett is a potential 1st round draft choice who opted out for risk of injury. All Picket did this season was throw for 4319 yards and 42 touchdowns. Michigan State will be without star running back Kenneth Walker III. Walker rushed for 1646 yards and 18 touchdowns this season while averaging a lofty 6.2 yards per carry.

It comes down to this for me when handicapping this game. Which difference can make the difference between winning and losing? The answer to this then becomes simple. I unequivocally trust Pitt’s defense more than that of today’s opponent. Pitt is #40 in total defense, #6 in rush defense, and #2 in sacks nationally. Conversely, Michigan State is #117 out of 130 college football FBS teams in total defense and dead last in pass yards allowed. Bet Pittsburgh plus the points for a Top Play wager.