(NFL) LA Rams vs. Indianapolis, 09/19/2021 1:00 PM, Score: 27 - 24
Point Spread: -3.50 | -110.00 LA Rams (Away)
Result: Loss
This is an 8* on LA RAMS

The Rams looked very impressive Sunday night when they beat the Bears 34-14 as a nine-point favorite. New QB Matt Stafford looked right at home in Sean McVay’s offense as the former Lion threw for 321 yards and three touchdowns. Stafford could be in line for another 300-plus yard day this week, or at least close to that, when he faces a Colts secondary that just gave up four touchdown passes to Russell Wilson. In sharp contrast to the Rams, Indy looked bad in a 28-16 opening week loss. Carson Wentz, not long removed from foot surgery, was a sitting duck behind an offensive line that played poorly. The Rams have Aaron Donald so Wentz is likely to be under duress yet again this week. Worth noting is that the Colts have never covered in four previous tries as a home underdog under Frank Reich. McVay is 8-3 straight up and against the spread as a favorite of -3.5 to -9.5. You’ve got to be careful not to overreact to one week, but the Rams looked really good in Week 1 and the Colts simply did not. The Rams have also been a really good road team during McVay’s time here, winning 23 of 34 games. They have been perfect in road openers the last four years averaging over 30 points/game. Lay it! Play on LOS ANGELES